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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd1f40dcef09bb41dd39c613c4c4a7a122d94e779a8a57fb10ad00f6380c2279a' 
  AND token = 'Zz4f5mYN6LhBQZY0cj4/Hci1B67aCaYzg67v6kq6t6E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}