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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f114da716b13502da8a895ba41531d4a3009358674be3e411f1a5e43953a02e0' 
  AND token = '2rpUXo4nZ2Me267X5ltHZ3KwOL37tUpEh+/CqIqRhiQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}