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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e4f901317ad1fb5fffebc8c66208629a540053a023da3a33b1329442eb1c2e52' 
  AND token = '3+0MmbKmCYyud1Kx4fn2JjLfeS79h5/e7XjnplJYpRo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00012

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}